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Whom it may be suitable for: Those whose depression causes fatigue; also ideal for anxiety symptoms and anxiety disorders; not ideal where weight gain is a health concern.
Pros: A very effective SSRI that can be easier to start and stay on than others.
Side effects: Jitteriness, insomnia, headaches, dry mouth, nausea (and, rarely, risk of seizure).
Whom it may be suitable for: Not an ideal first-line treatment: Start-up can be difficult to tolerate, and serotonin is often needed to effect mood change.
Side effects: Nausea, insomnia, headaches, sexual dysfunction, jitteriness; possibly drowsiness, dry mouth, constipation.
It’s the worst one for weight gain, and among the worst for withdrawal symptoms (unless properly managed).
Pros: This SSRI has fewer overall side effects than some antidepressants, but the serotonin-related side effects can be powerful.